Lori Sussel, PhDPrincipal InvestigatorDirector of Basic and Translational Research, Barbara Davis CenterSissel and Findlow Family Chair

Lori Sussel, PhD

Principal Investigator

Director of Basic and Translational Research, Barbara Davis Center

Sissel and Findlow Family Chair

Elliott Brooks, BSGraduate StudentCell identity is often established through specific epigenetic and transcriptional signatures that can be driven by transcription factor expression and their co-factors. My project will focus on the molecular roles …

Elliott Brooks, BS

Graduate Student

Cell identity is often established through specific epigenetic and transcriptional signatures that can be driven by transcription factor expression and their co-factors. My project will focus on the molecular roles of transcription factor function in the differentiation and identity of pancreatic alpha and beta cells using mouse models and in vitro molecular techniques. Understanding the genetics and epigenetics in establishing and maintaining islet cell identity could provide insights into the cellular pathology of diabetes.

Dylan Sarbaugh, BS

Graduate Student

I am characterizing the role of the Chromodomain-helicase-DNA-binding protein 4 (Chd4) in the proper development and function of pancreatic beta cells. It has been shown that Chd4 acts in the Nucleosome Remodeling and Deacetylase (NuRD) complex, where it facilitates nucleosome remodeling through Chd4’s ATPase domain, leading to transcriptional repression of specific genes. Our preliminary data demonstrates Chd4 is integral to the proper development and function of beta cells and plays critical roles in maintaining gene repression that promotes proper adult beta cell function. My project will more clearly define the role of Chd4 via the NuRD complex during development and function of pancreatic beta cells.

Maria Hansen, MS

Graduate Student

Chris Schaaf, BS

Graduate Student

Bryce Hopwood, BS

Lab Manager

Tori, Hoelscher, MS

Professional Research Assistant

Past Lab Members

Michelle Guney, PhD, Research Instructor

Yongkyung Kim, PhD, Postdoctoral Fellow

Laura Hudish, PhD, Postdoctoral Fellow

David Lorberbaum, PhD, Postdoctoral Fellow, Assistant Professor, University of Michigan

Elena Abarinov, PhD, Graduate Student, Postdoctoral Fellow

Alex Theis, PhD, Graduate Student

Nicole Moss, PhD, Graduate Student, currently a Postdoctoral Fellow at Duke University in the lab of Dr. Debby Silver

Ruth Singer, PhD, Graduate Student, currently a Postdoctoral Fellow at The Rockefeller University in the lab of Dr. Robert Darnell

Shouhong Xuan, Research Scientist

Cailin Deiter, BS, Professional Research Assistant, Current PhD Student at University of Colorado Anschutz Medical Campus

Charlie Moffatt, BS, RBI Summer Intern, Current PhD Student at University of Colorado Anschutz Medical Campus

Jay-Ho Chung, BS, Gates Summer Intership Program Summer Intern (GSIP), Middlebury College

Mary Claire Howell, Gates Summer Intership Program Summer Intern (GSIP), Davidson College

Amira Shiekh, Undergraduate Student Research Assistant, University of Colorado Boulder

McKenna Casey, Undergraduate Student Research Assistant, Colorado College

Helen Moses, Undergraduate Student Research Assistant, Carleton College

Jordan Reichers, BS, Student Research Assistant

Eloise Aragon, BS, Student Research Assistant