Publications


1. Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development. Churchill AJ, Gutiérrez GD, Singer RA, Lorberbaum DS, Fischer KA, Sussel L.
eLife. 2017; 6. PubMed [journal] PMID: 28071588, PMCID: PMC5224921


2. Pancreatic β cell identity requires continual repression of non-β cell programs. Gutiérrez GD, Bender AS, Cirulli V, Mastracci TL, Kelly SM, Tsirigos A, Kaestner  KH, Sussel L. The Journal of clinical investigation. 2017; 127(1):244-259. PubMed [journal] PMID: 27941248, PMCID: PMC5199704


3. The novel enterochromaffin marker Lmx1a regulates serotonin biosynthesis in enteroendocrine cell lineages downstream of Nkx2.2. Gross S, Garofalo DC, Balderes DA, Mastracci TL, Dias JM, Perlmann T, Ericson J, Sussel L. Development (Cambridge, England). 2016; 143(14):2616-28. PubMed [journal] PMID: 27287799, PMCID: PMC4958331

 


4. βlinc1 encodes a long noncoding RNA that regulates islet β-cell formation and function. Genes & Development. Arnes L, Akerman I, Balderes DA, Ferrer J, Sussel L. 2016; 30(5):502-7. PubMed [journal] PMID: 26944677, PMCID: PMC4782045


5. GATA4 and GATA6 regulate pancreatic endoderm identity through inhibition of hedgehog signaling. Xuan S, Sussel L. Development (Cambridge, England). 2016; 143(5):780-6. PubMed [journal] PMID: 26932670, PMCID: PMC4813334


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